A leading academic health system replaced ad-hoc, manually managed research computing with a governed Trusted Research Environment built on AWS and Research Gateway.
The customer is one of the nation’s premier academic medical centers, supporting hundreds of researchers conducting studies involving protected health information (PHI), clinical datasets, genomics, medical imaging, and other highly sensitive research data.
As research programs expanded across multiple departments and business units, the institution required a modern cloud platform that would enable researchers to leverage AWS while maintaining strict institutional security policies and governance requirements.
The institution sought a Trusted Research Environment (TRE) that would provide secure, isolated research workspaces while ensuring sensitive data remained protected throughout its lifecycle—from data ingestion to researcher collaboration and controlled data export.
Relevance Lab partnered with the academic medical center to deploy a customized implementation of Research Gateway that provided secure research environments, automated governance workflows, and simplified administration across the organization.
Business Challenge
The institution needed to provide researchers with scalable cloud-based research environments while satisfying stringent institutional security, compliance, and operational requirements.
Trusted Research Environment Blueprint
Explore the Trusted Research Environment architecture, Research Gateway deployment, governed data ingress/egress workflows, role-based governance model, implementation methodology, and business outcomes behind this biomedical research cloud modernization.
View the Full Case StudyBusiness Challenges
Solution
Architecture Highlights
Secure Research Platform with Centralized Governance
Researchers access Research Gateway through the institution’s internal network, where authenticated users provision secure research workspaces using institution-approved catalog offerings.
Research Gateway orchestrates AWS infrastructure while enforcing governance policies, approval workflows, and role-based access controls.
Business Outcomes
Research Gateway: Built for Modern Research Computing
Relevance Lab helps academic medical centers and research institutions replace manual, compliance-heavy research provisioning with a governed Trusted Research Environment on AWS. Our expertise covers Research Gateway deployment, HIPAA-aligned security controls, approval-driven data ingress and egress workflows, and role-based governance for research administrators, researchers, and project owners.
We combine deep AWS platform knowledge with hands-on experience in biomedical and clinical research computing, helping institutions standardize research workspaces, reduce dependency on Research IT for routine requests, and give scientists secure, self-service access to the compute they need.