Trusted Research Environments using Research Gateway
In 2026, Trusted Research Environments (TREs) have become essential for organizations handling sensitive research data while pursuing new grants, collaborations, and regulated innovation. Increasing compliance requirements such as National Institute of Standards and Technology NIST 800-171 Rev.2, Cybersecurity Maturity Model Certification CMMC, U.S.
Department of Health and Human Services HIPAA, and Federal Information Security Modernization Act FISMA are now key enablers for accessing research funding, protecting participant data, and accelerating secure collaboration.
To address this need, RL has partnered with Amazon Web Services to deliver an integrated TRE solution combining AWS Landing Zone Accelerator (LZA), Universal Configurations, and the Research Gateway TRE platform.
This video demonstrates the end-to-end journey of deploying a modern TRE that makes cloud research with sensitive data frictionless, secure, and cost-effective. Customers can launch in weeks and gain an enterprise-grade environment that integrates into existing cloud estates with strong governance, compliance, and cost control from day one.
In this video, you will discover:
- How Trusted Research Environments (TREs) are implemented within Secure Research Portal (SRP) on AWS
- How a Principal Investigator sets up projects with embedded governance and controlled access
- How study data is structured, stored in S3, and linked to secure research projects
- How researchers securely upload and ingest data into isolated environments
- How TRE workspaces are provisioned using self-service controls and configured for analysis
- How researchers work within structured ingress, study, and egress environments
- How the Egress Request workflow ensures all data leaving the environment is reviewed, approved, and logged
Why It Matters
Most organizations treat security and productivity as competing priorities in regulated research environments.
That’s a flawed model.
By extending SRP with Research Gateway, organizations can:
- Deliver secure, isolated environments for sensitive data
- Enforce governance through policy-driven controls and structured access
- Ensure every data movement is reviewed, approved, and auditable
- Provide researchers with self-service capabilities without bypassing controls
- Meet compliance and audit requirements without introducing operational friction
The result is a scalable, compliant, and researcher-friendly secure research platform on AWS.
Ready to Operationalize Trusted Research Environments on AWS?
Connect with our experts to explore how Research Gateway can help you implement secure, governed, and scalable research platforms.